Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_0234Phosphopantetheinyl transferase. (214 aa)    
Predicted Functional Partners:
MCP_0233
Similar to peptide synthetase AdpD in Anabaena circinalis 90 (Q9K5L9).
  
 0.995
MCP_2673
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
     
  0.900
MCP_0232
Putative acyl-CoA synthetase.
  
  
 0.841
MCP_0231
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF849, prokaryotic family (IPR008567).
       0.727
MCP_0235
Conserved hypothetical protein.
     
 0.668
pycA
Putative pyruvate carboxylase subunit A.
     
 0.617
MCP_2920
Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.599
MCP_0028
Glyoxalase family protein.
  
 
 0.580
MCP_1150
Glyoxalase family protein.
  
 
 0.580
MCP_0230
Putative dolichyl-phosphate beta-glucosyltransferase.
       0.446
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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