STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
MCP_0258Putative geranylgeranylglyceryl diphosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (226 aa)    
Predicted Functional Partners:
MCP_2782
Putative (S)-2,3-Di-O-geranylgeranylglyceryl phosphate synthase.
 
  
 0.952
egsA
Glycerol-1-phosphate dehydrogenase [NAD(P)]; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
  
  
 0.931
MCP_1672
Conserved hypothetical protein.
    
 0.925
MCP_2780
Putative geranylgeranylglyceryl diphosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
  
  
 
0.901
MCP_2047
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF1405 family (IPR009845).
  
     0.675
MCP_2048
Conserved hypothetical protein; Similar to YvoF protein in Bacillus subtilis (O34993).
 
   
 0.560
MCP_0257
Putative TrmB family transcriptional regulator.
       0.503
MCP_0259
GTP-binding protein.
       0.453
cbiZ
Putative adenosylcobinamide amidohydrolase.
  
     0.452
MCP_0962
Putative ATP-dependent DNA helicase.
  
  
 0.408
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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