nadE-1 protein (Methanocella paludicola) - STRING interaction network

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nadE-1

NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (268 aa)

Predicted Functional Partners:

MCP_2311

0.940

ppnK

0.936

nadE-2

0.913

MCP_2438

0.670

MCP_0271

0.571

pycA

0.536

MCP_0949

0.426

Your Current Organism:

Methanocella paludicola

NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCP_0271	nadE-1	MCP_0271	MCP_0270	Conserved hypothetical protein; Contains one Protein of unknown function DUF6, transmembrane domain (IPR000620).	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.571
MCP_0949	MCP_2438	MCP_0949	MCP_2438	Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).	Asparagine synthase.	0.878
MCP_0949	nadE-1	MCP_0949	MCP_0270	Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.426
MCP_0949	nadE-2	MCP_0949	MCP_0445	Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).	NH(3)-dependent NAD(+) synthetase.	0.426
MCP_0949	pycA	MCP_0949	MCP_0184	Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).	Putative pyruvate carboxylase subunit A.	0.618
MCP_2311	nadE-1	MCP_2311	MCP_0270	Nicotinamide-nucleotide adenylyltransferase.	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.940
MCP_2311	nadE-2	MCP_2311	MCP_0445	Nicotinamide-nucleotide adenylyltransferase.	NH(3)-dependent NAD(+) synthetase.	0.930
MCP_2311	ppnK	MCP_2311	MCP_1736	Nicotinamide-nucleotide adenylyltransferase.	Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.927
MCP_2438	MCP_0949	MCP_2438	MCP_0949	Asparagine synthase.	Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).	0.878
MCP_2438	nadE-1	MCP_2438	MCP_0270	Asparagine synthase.	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.670
MCP_2438	nadE-2	MCP_2438	MCP_0445	Asparagine synthase.	NH(3)-dependent NAD(+) synthetase.	0.670
MCP_2438	ppnK	MCP_2438	MCP_1736	Asparagine synthase.	Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.623
MCP_2438	pycA	MCP_2438	MCP_0184	Asparagine synthase.	Putative pyruvate carboxylase subunit A.	0.721
nadE-1	MCP_0271	MCP_0270	MCP_0271	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Conserved hypothetical protein; Contains one Protein of unknown function DUF6, transmembrane domain (IPR000620).	0.571
nadE-1	MCP_0949	MCP_0270	MCP_0949	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).	0.426
nadE-1	MCP_2311	MCP_0270	MCP_2311	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Nicotinamide-nucleotide adenylyltransferase.	0.940
nadE-1	MCP_2438	MCP_0270	MCP_2438	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Asparagine synthase.	0.670
nadE-1	nadE-2	MCP_0270	MCP_0445	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	NH(3)-dependent NAD(+) synthetase.	0.913
nadE-1	ppnK	MCP_0270	MCP_1736	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.936
nadE-1	pycA	MCP_0270	MCP_0184	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Putative pyruvate carboxylase subunit A.	0.536

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