Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCP_0292Conserved hypothetical protein. (286 aa)    
Predicted Functional Partners:
MCP_0293
Phosphoserine phosphatase.
    
 0.989
MCP_1516
Archaeosine tRNA-ribosyltransferase.
 
   
 0.871
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.858
MCP_0291
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF373 family (IPR007254).
 
     0.773
MCP_0003
Conserved hypothetical protein.
  
     0.694
MCP_2850
Conserved hypothetical protein.
  
     0.694
MCP_1018
Conserved hypothetical protein.
 
     0.693
MCP_0048
Conserved hypothetical protein.
  
     0.692
MCP_2849
Putative single-stranded DNA-binding replication protein.
 
     0.689
MCP_1751
Conserved hypothetical protein; Similar to JAMM-like protein in Archaeoglobus fulgidus (O28085, AF_2198).
  
     0.688
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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