| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCP_0293 | MCP_2438 | MCP_0293 | MCP_2438 | Phosphoserine phosphatase. | Asparagine synthase. | 0.730 |
| MCP_0293 | glyA | MCP_0293 | MCP_0294 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.988 |
| MCP_0293 | trpA | MCP_0293 | MCP_2907 | Phosphoserine phosphatase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.912 |
| MCP_0293 | trpB | MCP_0293 | MCP_2908 | Phosphoserine phosphatase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.933 |
| MCP_2438 | MCP_0293 | MCP_2438 | MCP_0293 | Asparagine synthase. | Phosphoserine phosphatase. | 0.730 |
| MCP_2438 | glyA | MCP_2438 | MCP_0294 | Asparagine synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
| MCP_2438 | pdhD | MCP_2438 | MCP_1720 | Asparagine synthase. | Putative pyruvate dehydrogenase E3 component; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.527 |
| MCP_2438 | purA | MCP_2438 | MCP_0279 | Asparagine synthase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.981 |
| MCP_2438 | purB | MCP_2438 | MCP_2428 | Asparagine synthase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.972 |
| MCP_2438 | purT-1 | MCP_2438 | MCP_2477 | Asparagine synthase. | Phosphoribosylglycinamide formyltransferase 2. | 0.805 |
| MCP_2438 | thyA | MCP_2438 | MCP_1209 | Asparagine synthase. | Thymidylate synthase. | 0.682 |
| MCP_2438 | trpA | MCP_2438 | MCP_2907 | Asparagine synthase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.725 |
| MCP_2438 | trpB | MCP_2438 | MCP_2908 | Asparagine synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.688 |
| fae/hps | glyA | MCP_2904 | MCP_0294 | Formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.931 |
| glyA | MCP_0293 | MCP_0294 | MCP_0293 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase. | 0.988 |
| glyA | MCP_2438 | MCP_0294 | MCP_2438 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Asparagine synthase. | 0.928 |
| glyA | fae/hps | MCP_0294 | MCP_2904 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. | 0.931 |
| glyA | pdhD | MCP_0294 | MCP_1720 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative pyruvate dehydrogenase E3 component; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.936 |
| glyA | purA | MCP_0294 | MCP_0279 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.926 |
| glyA | purB | MCP_0294 | MCP_2428 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.947 |