Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_0358Peptidase M48, Ste24p family protein. (291 aa)    
Predicted Functional Partners:
MCP_0632
Conserved hypothetical protein; Contains one Amino acid-binding ACT domain (IPR002912).
  
    0.726
MCP_2676
Conserved hypothetical protein; Belongs to the GHMP kinase-like, archaeal family (IPR012043).
  
    0.696
MCP_2148
Conserved hypothetical protein; Belongs to the Auxin efflux carrier family (IPR004776).
  
  
 0.671
ilvD-1
Dihydroxy-acid dehydratase.
  
 
 0.613
ilvD-2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.613
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.611
MCP_0359
Hypothetical protein.
       0.532
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.515
lon
ATP-dependent protease La; Belongs to the peptidase S16 family.
  
 
 0.475
MCP_0360
Hypothetical protein; Contains at least one PBS lyase HEAT-like repeat (IPR004155).
       0.468
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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