Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
MCP_0360Hypothetical protein; Contains at least one PBS lyase HEAT-like repeat (IPR004155). (163 aa)    
Predicted Functional Partners:
MCP_1142
Hypothetical protein; Contains at least one PBS lyase HEAT-like repeat (IPR004155).
 
     0.704
MCP_2755
Hypothetical protein; Contains at least one PBS lyase HEAT-like repeatrepeat (IPR004155).
 
     0.703
MCP_2031
Conserved hypothetical protein; Contains at least PBS lyase HEAT-like repeat (IPR004155).
 
     0.701
MCP_2922
Hypothetical protein; Contains at least one PBS lyase HEAT-like repeat (IPR004155).
 
     0.697
MCP_1681
Hypothetical protein; Contains at least two PBS lyase HEAT-like repeats (IPR004155).
 
     0.696
MCP_2391
Hypothetical protein; Contains two PBS lyase HEAT-like repeats (IPR004155).
  
     0.690
MCP_1210
Conserved hypothetical protein; Contains the PBS lyase HEAT-like repeat (IPR004155).
  
     0.688
MCP_0359
Hypothetical protein.
       0.671
MCP_1395
Hypothetical protein.
 
     0.658
cbiX-1
Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
       0.512
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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