STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_0363Conserved hypothetical protein. (368 aa)    
Predicted Functional Partners:
nifH-1
Putative nitrogenase iron protein.
 
 0.996
MCP_0362
Conserved hypothetical protein.
 
  
 0.994
cobB
Probable cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
    
 0.981
cbiX-1
Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
 
   
 0.883
nifH-2
Putative nitrogenase iron protein; Belongs to the NifH/BchL/ChlL family.
 
 
 0.849
atw-2
Putative methylcoenzyme M reductase system component A2.
 
  
 0.708
atw-1
Putative methylcoenzyme M reductase system component A2.
 
  
 0.707
MCP_1063
Putative CoA enzyme activase.
  
     0.686
MCP_0267
Conserved hypothetical protein; Contains one Phosphate acetyl/butaryl transferase domain (IPR002505); Similar to Putative methyltransferase mtx subunit X in Methanosarcina barkeri (strain Fusaro / DSM 804) (O32853).
  
   
 0.663
MCP_0554
Conserved hypothetical protein; Contains one YcaO_like domain (IPR003776).
  
     0.620
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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