Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_0377Peptidase S54, rhomboid family protein; Contains one Zinc finger, AN1-type domain (IPR000058). (261 aa)    
Predicted Functional Partners:
MCP_2736
Conserved hypothetical protein.
 
 0.808
MCP_1835
Conserved hypothetical protein; Belongs to the Band 7 protein family (IPR001107); Belongs to the Stomatin family (IPR001972).
  
 0.780
MCP_2469
Conserved hypothetical protein; Contains one Dynamin, GTPase region domain (IPR001401).
   
 
 0.702
tatA
Putative sec-independent translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
  
 
 0.682
MCP_1559
Putative sec-independent translocase protein.
  
 
 0.682
MCP_2809
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF88 family (IPR002790).
 
   
 0.659
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
 
     0.647
birA
Biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase; Bifunctional protein.
     
 0.642
MCP_0989
Glutamate synthase.
 
   
 0.640
MCP_0379
Putative biotin synthesis protein BioY.
       0.604
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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