Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCP_0381Putative cobalt ABC transporter ATP binding protein. (264 aa)    
Predicted Functional Partners:
MCP_0382
Putative cobalt ABC transporter.
 
 0.996
MCP_0379
Putative biotin synthesis protein BioY.
 
 
 0.993
MCP_0380
Putative cobalt ABC transporter ATP binding protein.
 
  
 
0.981
MCP_1306
Putative cobalt ABC transporter.
 
 0.977
MCP_1561
Putative peptide ABC transporter ATP binding protein.
   
0.834
birA
Biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase; Bifunctional protein.
 
    0.808
MCP_0798
Putative cobalt ABC transporter permease protein.
 
 
 0.773
MCP_1084
Putative cobalt ABC transporter permease protein.
  
 
 0.744
MCP_0377
Peptidase S54, rhomboid family protein; Contains one Zinc finger, AN1-type domain (IPR000058).
       0.604
rpl5p
50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
 
  
 0.587
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.