Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
serAD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)    
Predicted Functional Partners:
apgM-1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.905
apgM-2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.905
apgM-3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase.
    
 0.905
MCP_2438
Asparagine synthase.
  
  
 0.747
MCP_0084
Putative histone deacetylase.
 
 
 0.679
MCP_1774
Hypothetical protein; Contains at least one Ankyrin repeatrepeat (IPR002110); Contains at least one PBS lyase HEAT-like repeat (IPR004155).
   
 0.662
MCP_0933
Hypothetical protein; Contains at least one Ankyrin repeat (IPR002110).
   
 0.636
rpl14p
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
 
   0.628
rpl13p
50S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.620
MCP_0952
Hypothetical protein; Contains one Glycosyl transferase, family 2 domain (IPR001173); Contains one Phosphoglycerate mutase domain (IPR013078).
  
  
 0.618
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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