STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_0405Putative HTH-type transcriptional regulator. (123 aa)    
Predicted Functional Partners:
MCP_1816
Conserved hypothetical protein; Involved in DNA damage repair.
 
     0.688
MCP_2590
Conserved hypothetical protein; Involved in DNA damage repair.
 
     0.653
MCP_0407
Truncated threonyl-tRNA synthetase.
 
     0.562
MCP_0404
Conserved hypothetical protein; Contains one YHS domain (IPR007029); Contains one TRASH domain (IPR011017).
       0.543
MCP_0406
Hypothetical protein.
       0.532
iscS-1
Probable cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
     0.483
MCP_0409
Putative iron sulfur cluster assembly protein.
 
     0.477
MCP_0401
Putative ABC transporter.
 
     0.451
pfdA
Prefoldin alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
     0.446
cdc6-2
Cell division control protein 6 homolog; Involved in regulation of DNA replication.
  
     0.444
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.