Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_0436Putative thiamine-monophosphate kinase. (328 aa)    
Predicted Functional Partners:
MCP_0437
Isocitrate/isopropylmalate dehydrogenase family protein.
       0.762
MCP_0267
Conserved hypothetical protein; Contains one Phosphate acetyl/butaryl transferase domain (IPR002505); Similar to Putative methyltransferase mtx subunit X in Methanosarcina barkeri (strain Fusaro / DSM 804) (O32853).
 
     0.727
MCP_1957
Conserved hypothetical protein; Contains one Elongator protein 3/MiaB/NifB domain (IPR006638); Contains one Radical SAM domain (IPR007197).
 
     0.668
rfcL
Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
 
     0.646
MCP_1943
Conserved hypothetical protein; Contains one MoaA/nifB/pqqE, iron-sulphur binding domain (IPR000385); Contains one Radical SAM domain (IPR007197).
       0.582
pgk-1
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
       0.529
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
       0.529
MCP_0699
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF366 family (IPR007162).
       0.529
MCP_0266
Conserved hypothetical protein.
  
     0.519
MCP_2960
Conserved hypothetical protein.
       0.464
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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