STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
atw-1Putative methylcoenzyme M reductase system component A2. (527 aa)    
Predicted Functional Partners:
mcrA
Methyl-coenzyme M reductase alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
   
 0.980
mcrG
Methyl-coenzyme M reductase gamma subunit.
   
  0.977
mcrC
Methyl-coenzyme M reductase operon protein C.
   
 0.976
mcrB
Methyl-coenzyme M reductase beta subunit.
   
  0.966
MCP_1562
Putative peptide ABC transporter permease protein.
 
 0.953
mcrD-1
Methyl-coenzyme M reductase operon protein D.
    
 0.933
mcrD-2
Methyl-coenzyme M reductase operon protein D.
    
 0.913
atw-2
Putative methylcoenzyme M reductase system component A2.
  
  
 
0.901
MCP_0519
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF134 family (IPR002852).
  
    0.898
MCP_1563
Putative peptide ABC transporter permease protein.
 
 
 0.833
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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