STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_0523[NiFe]-hydrogenase large subunit; Similar to Ech hydrogenase, subunit EchE in Methanosarcina barkeri (O59656). (359 aa)    
Predicted Functional Partners:
echC
Ech hydrogenase subunit C.
 
 0.997
MCP_2637
Putative [NiFe]-hydrogenase small subunit.
 
 0.982
echB
Ech hydrogenase subunit B.
 
 
 0.972
echF
Ech hydrogenase subunit F.
 
 
 0.912
pyrK
Probable dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
     
 0.877
MCP_2638
4Fe-4S ferredoxin, iron-sulfur binding protein.
 
 
 0.860
hdrA/mvhD
CoB--CoM heterodisulfide reductase iron-sulfur subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
     
 0.842
MCP_0617
4Fe-4S ferredoxin, iron-sulfur binding protein.
  
 
 0.828
hypB
Putative hydrogenase nickel incorporation protein HypB.
   
 
 0.798
MCP_0521
Nucleotide-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
     
 0.788
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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