Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MCP_0587Ammonium transporter. (413 aa)    
Predicted Functional Partners:
MCP_0588
Putative nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
  
 
 0.968
MCP_0586
Putative nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.965
MCP_0431
Putative nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.900
dnaK
Heat shock protein 70; Acts as a chaperone.
  
 
 0.715
MCP_2438
Asparagine synthase.
     
 0.674
rocF
Arginase; Belongs to the arginase family.
  
  
 0.674
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.672
dnaJ
Heat shock protein 40; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...]
     
 0.669
MCP_0636
Thermosome; Belongs to the TCP-1 chaperonin family.
     
 0.657
MCP_0664
Thermosome; Belongs to the TCP-1 chaperonin family.
     
 0.657
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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