Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_0710Glutamate synthase large subunit domain 1. (364 aa)    
Predicted Functional Partners:
MCP_0708
Glutamate synthase large subunit domain 3.
  
 0.997
MCP_0709
Glutamate synthase large subunit domain 2; Belongs to the glutamate synthase family.
 
 
 0.992
MCP_0989
Glutamate synthase.
  
 
 0.992
MCP_1678
Conserved hypothetical protein.
  
 
 0.789
fwdC-1
Tungsten-containing formylmethanofuran dehydrogenase subunit C.
 
 
 0.717
fwdC-2
Tungsten-containing formylmethanofuran dehydrogenase subunit C.
 
 
 0.711
MCP_2438
Asparagine synthase.
  
  
 0.650
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.641
MCP_0707
Hypothetical protein.
       0.566
frhB-1
Putative coenzyme F420 hydrogenase subunit beta.
  
    0.556
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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