Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_0810Conserved hypothetical protein; Contains two Protein of unknown function DUF6, transmembrane domains (IPR000620). (312 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase.
       0.775
MCP_0811
Putative flavodoxin.
       0.655
MCP_0812
Conserved hypothetical protein; Contains two Protein of unknown function DUF6, transmembrane domains (IPR000620).
 
    
0.629
MCP_0808
Conserved hypothetical protein.
       0.625
MCP_1485
Conserved hypothetical protein.
   
 
 0.604
MCP_0807
Putative signaling protein; Contains three PAS domains (IPR000014); Contains one PAS-associated, C-terminal domain (IPR000700).; Contains one PAC motif repeat (IPR001610).
 
     0.603
carS
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
   
   0.518
carS-2
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
   
   0.518
MCP_2668
Putative Na(+)/H(+) antiporter.
 
  
 0.438
MCP_2743
Putative amino acid ABC transporter permease protein; Contains one PEGA domain (IPR013229).
 
  
 0.436
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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