Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_0918uracil-DNA glycosylase. (182 aa)    
Predicted Functional Partners:
MCP_1451
Putative endonuclease III.
 
   
 0.623
MCP_1091
Putative endonuclease IV.
 
   
 0.588
MCP_1129
Exodeoxyribonuclease.
  
  
 0.543
MCP_0919
Conserved hypothetical protein.
     
 0.541
MCP_1946
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF99 family (IPR002802).
       0.536
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
       0.532
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.529
MCP_1376
Putative TrmB family transcriptional regulator.
       0.529
MCP_0033
Putative 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family.
     
 0.512
pycB
Pyruvate carboxylase subunit B.
  
    0.461
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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