STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Coexpression
Experiments
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[Homology]
Score
rbcLRibulose bisphosphate carboxylase. (395 aa)    
Predicted Functional Partners:
MCP_2142
Ribose-1,5-bisphosphate isomerase; Belongs to the eIF-2B alpha/beta/delta subunits family.
 
  
 0.966
MCP_0060
Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
 
   
 0.932
MCP_1151
Putative phosphohydrolase.
 
  
 0.922
pgk-1
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.919
pgk-2
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.919
MCP_2975
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
  0.901
MCP_0030
Conserved hypothetical protein.
   
 
 0.836
acdA
acetyl-CoA synthetase alpha subunit.
      
 0.633
csl4
Putative 3'-5' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
      
 0.628
rrp42
Probable exosome complex exonuclease 2; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
      
 0.624
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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