STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tgtA7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (487 aa)    
Predicted Functional Partners:
MCP_2857
Archaeosine tRNA-ribosyltransferase.
     0.952
MCP_1181
Conserved hypothetical protein.
  
  
 0.663
MCP_1516
Archaeosine tRNA-ribosyltransferase.
 
  
0.649
MCP_1179
Putative histidine kinase; Contains two PAS domains (IPR000014); Contains two PAS-associated, C-terminal domains (IPR000700).; Contains one GAF domain (IPR003018).; Contains one ATP-binding region, ATPase-like domain (IPR003594).; Contains two PAC motif repeats (IPR001610).
  
  
 0.648
MCP_1182
Conserved hypothetical protein; Belongs to the ShortTriphosphoribosyl-dephospho-CoA protein family (IPR002736).
       0.556
MCP_1183
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF447 family (IPR007386).
       0.556
truB
Probable tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.555
MCP_0949
Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).
       0.529
dtdA
D-tyrosyl-tRNA(Tyr) deacylase/cell division protein FtsZ homolog; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo; Belongs to the FtsZ family.
  
  
 0.529
hisS
histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.508
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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