STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_1186Conserved hypothetical protein; Belongs to the Protein of unknown function DUF116 family (IPR002829). (241 aa)    
Predicted Functional Partners:
MCP_1185
Hypothetical protein.
       0.648
iorA
Indolepyruvate oxidoreductase subunit IorA; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
       0.538
iorB
Indolepyruvate oxidoreductase subunit IorB.
       0.538
cbiX-1
Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
 
     0.420
MCP_0190
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF63 family (IPR002749).
  
   
 0.409
MCP_1957
Conserved hypothetical protein; Contains one Elongator protein 3/MiaB/NifB domain (IPR006638); Contains one Radical SAM domain (IPR007197).
 
     0.400
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.