STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_1324Conserved hypothetical protein; Contains one ATP-grasp fold, DUF201-type domain (IPR003806). (288 aa)    
Predicted Functional Partners:
MCP_1325
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF66 family (IPR002756); Belongs to the Hydantoinase/oxoprolinase family (IPR002821).
 
  
 0.997
mfnA
L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.924
MCP_0670
Putative amino acid kinase.
 
   
 0.888
MCP_1326
Conserved hypothetical protein.
       0.773
mfnB
Conserved hypothetical protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
 
   
 0.756
fwdA-1
Tungsten-containing formylmethanofuran dehydrogenase subunit A.
 
   
 0.730
fwdA-2
Tungsten-containing formylmethanofuran dehydrogenase subunit A.
 
   
 0.730
ftr
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
     0.691
comD/comE
Sulfopyruvate decarboxylase.
  
   
 0.681
fwdC-2
Tungsten-containing formylmethanofuran dehydrogenase subunit C.
 
     0.675
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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