STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_1350Putative histidine kinase; Contains three PAS domains (IPR000014); Contains two PAS-associated, C-terminal domains (IPR000700).; Contains one GAF domain (IPR003018).; Contains one ATP-binding region, ATPase-like domain (IPR003594).; Contains three PAC motif repeats (IPR001610). (842 aa)    
Predicted Functional Partners:
MCP_2581
Putative response regulator.
 
 
 0.901
MCP_2698
Protein kinase; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least three Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least five Tetratricopeptide TPR_2repeats (IPR013105).
   
 0.687
MCP_0475
Putative response regulator.
 
 
 0.662
MCP_2616
Putative histidine kinase; Contains at least one GAF domain (IPR003018); Contains one ATP-binding region, ATPase-like domain (IPR003594).; Contains one histidine kinase A, N-terminal domain (IPR003661).
  
   
 0.658
pdhB
Pyruvate dehydrogenase E1 component beta subunit.
   
 0.615
MCP_0444
Aldo/keto reductase family protein.
   
 0.589
MCP_1650
Putative response regulator.
 
 
 
 0.588
MCP_1351
Putative histidine kinase; Contains one PAS domain (IPR000014); Contains one PAS-associated, C-terminal domain (IPR000700).; Contains one ATP-binding region, ATPase-like domain (IPR003594).; Contains one Histidine kinase, HAMP region domain (IPR003660).
 
    
0.556
prs-1
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 0.460
prs-2
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
   
 0.460
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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