node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCP_1360 | MCP_1361 | MCP_1360 | MCP_1361 | Hypothetical protein. | Xanthine/uracil/vitamin C permease family protein. | 0.727 |
MCP_1361 | MCP_1360 | MCP_1361 | MCP_1360 | Xanthine/uracil/vitamin C permease family protein. | Hypothetical protein. | 0.727 |
MCP_1361 | MCP_2149 | MCP_1361 | MCP_2149 | Xanthine/uracil/vitamin C permease family protein. | Conserved hypothetical protein; Belongs to the Protein of unknown function UPF0132 family (IPR005348). | 0.808 |
MCP_1361 | apt | MCP_1361 | MCP_0400 | Xanthine/uracil/vitamin C permease family protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.649 |
MCP_1361 | purA | MCP_1361 | MCP_0279 | Xanthine/uracil/vitamin C permease family protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.535 |
MCP_1361 | purC | MCP_1361 | MCP_2558 | Xanthine/uracil/vitamin C permease family protein. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.615 |
MCP_1361 | purD | MCP_1361 | MCP_2597 | Xanthine/uracil/vitamin C permease family protein. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.627 |
MCP_1361 | purE | MCP_1361 | MCP_0125 | Xanthine/uracil/vitamin C permease family protein. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.610 |
MCP_1361 | purL | MCP_1361 | MCP_1797 | Xanthine/uracil/vitamin C permease family protein. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.584 |
MCP_1361 | purM | MCP_1361 | MCP_2729 | Xanthine/uracil/vitamin C permease family protein. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.542 |
MCP_1361 | purQ | MCP_1361 | MCP_1798 | Xanthine/uracil/vitamin C permease family protein. | Phosphoribosylformylglycinamidine synthase I. | 0.532 |
MCP_2149 | MCP_1361 | MCP_2149 | MCP_1361 | Conserved hypothetical protein; Belongs to the Protein of unknown function UPF0132 family (IPR005348). | Xanthine/uracil/vitamin C permease family protein. | 0.808 |
apt | MCP_1361 | MCP_0400 | MCP_1361 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Xanthine/uracil/vitamin C permease family protein. | 0.649 |
apt | purA | MCP_0400 | MCP_0279 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.852 |
apt | purC | MCP_0400 | MCP_2558 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.589 |
apt | purD | MCP_0400 | MCP_2597 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.565 |
apt | purE | MCP_0400 | MCP_0125 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.651 |
apt | purL | MCP_0400 | MCP_1797 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.624 |
apt | purM | MCP_0400 | MCP_2729 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.666 |
apt | purQ | MCP_0400 | MCP_1798 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylformylglycinamidine synthase I. | 0.625 |