Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (146 aa)    
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
 
 0.998
ribC
Riboflavin synthase.
 
  
 0.994
MCP_1048
2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino) pyrimidine reductase.
 
 
 0.942
metK
S-adenosylmethionine synthetase.
  
 
 0.921
aspC-1
Aspartate aminotransferase.
 
 
 0.915
aspC-2
Aspartate aminotransferase.
     
 0.898
MCP_1403
Putative large-conductance mechanosensitive channel.
  
  
 0.889
MCP_1651
Putative 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine reductase.
 
 
 0.862
ribL
Putative cytidyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
     
 0.832
pyrB
Aspartate carbamoyltransferase.
  
    0.815
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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