node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCP_0377 | nfi | MCP_0377 | MCP_1458 | Peptidase S54, rhomboid family protein; Contains one Zinc finger, AN1-type domain (IPR000058). | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.566 |
MCP_1449 | MCP_1451 | MCP_1449 | MCP_1451 | Conserved hypothetical protein; Belongs to the Protein of unknown function DUF82 family (IPR002782). | Putative endonuclease III. | 0.686 |
MCP_1449 | nfi | MCP_1449 | MCP_1458 | Conserved hypothetical protein; Belongs to the Protein of unknown function DUF82 family (IPR002782). | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.506 |
MCP_1451 | MCP_1449 | MCP_1451 | MCP_1449 | Putative endonuclease III. | Conserved hypothetical protein; Belongs to the Protein of unknown function DUF82 family (IPR002782). | 0.686 |
MCP_1451 | fen | MCP_1451 | MCP_2759 | Putative endonuclease III. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.582 |
MCP_1451 | nfi | MCP_1451 | MCP_1458 | Putative endonuclease III. | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.423 |
MCP_1456 | MCP_1459 | MCP_1456 | MCP_1459 | Hypothetical protein. | Conserved hypothetical protein. | 0.414 |
MCP_1456 | nfi | MCP_1456 | MCP_1458 | Hypothetical protein. | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.551 |
MCP_1456 | sepS | MCP_1456 | MCP_1457 | Hypothetical protein. | O-phosphoseryl-tRNA synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). | 0.551 |
MCP_1459 | MCP_1456 | MCP_1459 | MCP_1456 | Conserved hypothetical protein. | Hypothetical protein. | 0.414 |
MCP_1459 | nfi | MCP_1459 | MCP_1458 | Conserved hypothetical protein. | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.563 |
MCP_1459 | sepS | MCP_1459 | MCP_1457 | Conserved hypothetical protein. | O-phosphoseryl-tRNA synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). | 0.568 |
dnaJ | nfi | MCP_2018 | MCP_1458 | Heat shock protein 40; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.712 |
fen | MCP_1451 | MCP_2759 | MCP_1451 | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | Putative endonuclease III. | 0.582 |
fen | nfi | MCP_2759 | MCP_1458 | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.420 |
fen | nucS | MCP_2759 | MCP_1445 | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | Conserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. | 0.414 |
nfi | MCP_0377 | MCP_1458 | MCP_0377 | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | Peptidase S54, rhomboid family protein; Contains one Zinc finger, AN1-type domain (IPR000058). | 0.566 |
nfi | MCP_1449 | MCP_1458 | MCP_1449 | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | Conserved hypothetical protein; Belongs to the Protein of unknown function DUF82 family (IPR002782). | 0.506 |
nfi | MCP_1451 | MCP_1458 | MCP_1451 | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | Putative endonuclease III. | 0.423 |
nfi | MCP_1456 | MCP_1458 | MCP_1456 | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | Hypothetical protein. | 0.551 |