| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCP_0625 | metE | MCP_0625 | MCP_1359 | Putative S-adenosylmethionine synthetase. | Putative methylcobalamin:homocysteine methyltransferase. | 0.918 |
| MCP_0625 | metK | MCP_0625 | MCP_1463 | Putative S-adenosylmethionine synthetase. | S-adenosylmethionine synthetase. | 0.900 |
| MCP_0773 | MCP_2438 | MCP_0773 | MCP_2438 | Putative nucleotide sugar epimerase/dehydratase. | Asparagine synthase. | 0.405 |
| MCP_0773 | metK | MCP_0773 | MCP_1463 | Putative nucleotide sugar epimerase/dehydratase. | S-adenosylmethionine synthetase. | 0.795 |
| MCP_0863 | MCP_2438 | MCP_0863 | MCP_2438 | Putative nucleotide sugar epimerase/dehydratase. | Asparagine synthase. | 0.491 |
| MCP_0863 | metK | MCP_0863 | MCP_1463 | Putative nucleotide sugar epimerase/dehydratase. | S-adenosylmethionine synthetase. | 0.795 |
| MCP_1403 | metK | MCP_1403 | MCP_1463 | Putative large-conductance mechanosensitive channel. | S-adenosylmethionine synthetase. | 0.800 |
| MCP_1403 | ribH | MCP_1403 | MCP_1453 | Putative large-conductance mechanosensitive channel. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.889 |
| MCP_2438 | MCP_0773 | MCP_2438 | MCP_0773 | Asparagine synthase. | Putative nucleotide sugar epimerase/dehydratase. | 0.405 |
| MCP_2438 | MCP_0863 | MCP_2438 | MCP_0863 | Asparagine synthase. | Putative nucleotide sugar epimerase/dehydratase. | 0.491 |
| MCP_2438 | glyA | MCP_2438 | MCP_0294 | Asparagine synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.961 |
| MCP_2438 | metE | MCP_2438 | MCP_1359 | Asparagine synthase. | Putative methylcobalamin:homocysteine methyltransferase. | 0.786 |
| MCP_2438 | metK | MCP_2438 | MCP_1463 | Asparagine synthase. | S-adenosylmethionine synthetase. | 0.875 |
| MCP_2438 | pyrG | MCP_2438 | MCP_0497 | Asparagine synthase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.941 |
| ahcY | glyA | MCP_1344 | MCP_0294 | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.673 |
| ahcY | metE | MCP_1344 | MCP_1359 | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | Putative methylcobalamin:homocysteine methyltransferase. | 0.979 |
| ahcY | metK | MCP_1344 | MCP_1463 | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | S-adenosylmethionine synthetase. | 0.881 |
| glyA | MCP_2438 | MCP_0294 | MCP_2438 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Asparagine synthase. | 0.961 |
| glyA | ahcY | MCP_0294 | MCP_1344 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. | 0.673 |
| glyA | metE | MCP_0294 | MCP_1359 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative methylcobalamin:homocysteine methyltransferase. | 0.657 |