STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fgdSimilar to F420-dependent alcohol dehydrogenase Adf in Methanofollis liminatans (O93735) and Methanoculleus thermophilus (O93734). (336 aa)    
Predicted Functional Partners:
cofD
LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.755
cofE-1
F420-0:gamma-glutamyl ligase.
 
   
 0.728
cofE-2
F420-0:gamma-glutamyl ligase.
 
   
 0.728
MCP_0484
Putative glycoside hydrolase.
 
     0.582
MCP_1467
Belongs to the Conserved hypothetical protein 61 family (IPR004425).
  
  
 0.563
MCP_2522
ABC transporter permease protein.
 
  
 0.559
MCP_1468
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF473 family (IPR007417).
       0.542
MCP_1469
Conserved hypothetical protein.
       0.542
MCP_2523
ABC transporter ATP binding protein.
 
  
 0.542
cofG
FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
 
  
 0.540
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (20%) [HD]