| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCP_1404 | MCP_1504 | MCP_1404 | MCP_1504 | Putative diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Putative methyltransferase. | 0.677 |
| MCP_1404 | MCP_1507 | MCP_1404 | MCP_1507 | Putative diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | tRNA methyltransferase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.545 |
| MCP_1404 | apt | MCP_1404 | MCP_0400 | Putative diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.890 |
| MCP_1404 | csl4 | MCP_1404 | MCP_1505 | Putative diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Putative 3'-5' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.725 |
| MCP_1404 | pus10 | MCP_1404 | MCP_0722 | Putative diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 0.405 |
| MCP_1404 | rpoL | MCP_1404 | MCP_1506 | Putative diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.614 |
| MCP_1503 | MCP_1504 | MCP_1503 | MCP_1504 | Conserved hypothetical protein. | Putative methyltransferase. | 0.528 |
| MCP_1503 | MCP_1507 | MCP_1503 | MCP_1507 | Conserved hypothetical protein. | tRNA methyltransferase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.427 |
| MCP_1503 | MCP_1508 | MCP_1503 | MCP_1508 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.427 |
| MCP_1503 | csl4 | MCP_1503 | MCP_1505 | Conserved hypothetical protein. | Putative 3'-5' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.506 |
| MCP_1503 | rpoL | MCP_1503 | MCP_1506 | Conserved hypothetical protein. | DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.496 |
| MCP_1504 | MCP_1404 | MCP_1504 | MCP_1404 | Putative methyltransferase. | Putative diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.677 |
| MCP_1504 | MCP_1503 | MCP_1504 | MCP_1503 | Putative methyltransferase. | Conserved hypothetical protein. | 0.528 |
| MCP_1504 | MCP_1507 | MCP_1504 | MCP_1507 | Putative methyltransferase. | tRNA methyltransferase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.609 |
| MCP_1504 | MCP_1508 | MCP_1504 | MCP_1508 | Putative methyltransferase. | Conserved hypothetical protein. | 0.609 |
| MCP_1504 | MCP_2296 | MCP_1504 | MCP_2296 | Putative methyltransferase. | Conserved hypothetical protein; Contains one Uncharacterized domain 2 (IPR004521). | 0.652 |
| MCP_1504 | apt | MCP_1504 | MCP_0400 | Putative methyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.582 |
| MCP_1504 | csl4 | MCP_1504 | MCP_1505 | Putative methyltransferase. | Putative 3'-5' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.903 |
| MCP_1504 | pus10 | MCP_1504 | MCP_0722 | Putative methyltransferase. | Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 0.561 |
| MCP_1504 | pycA | MCP_1504 | MCP_0184 | Putative methyltransferase. | Putative pyruvate carboxylase subunit A. | 0.553 |