STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
hdrC-1CoB--CoM heterodisulfide reductase iron-sulfur subunit C. (181 aa)    
Predicted Functional Partners:
hdrA-1
CoB--CoM heterodisulfide reductase iron-sulfur subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.998
hdrB-1
CoB--CoM heterodisulfide reductase subunit B.
 
 0.998
hdrA-2
CoB--CoM heterodisulfide reductase iron-sulfur subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.995
hdrA/mvhD
CoB--CoM heterodisulfide reductase iron-sulfur subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.991
mvhD-1
F420-non-reducing hydrogenase iron-sulfur subunit D.
 
 
 0.985
hdrB-2
CoB--CoM heterodisulfide reductase subunit B.
  
  
 0.972
fdhB-1
Formate dehydrogenase beta chain.
 
 
 0.945
MCP_2642
Putative Fe-S cluster-binding oxidoreductase component; Similar to CoB--CoM heterodisulfide reductase subunit B HdrB in Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133) (Q50755).
 
 
 0.942
hdrB-3
CoB--CoM heterodisulfide reductase subunit B.
 
 
 0.942
mvhD-2
F420-non-reducing hydrogenase iron-sulfur subunit D.
 
 
 0.939
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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