Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (357 aa)    
Predicted Functional Partners:
MCP_1638
Isopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
 
  
 0.995
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
  
 0.975
MCP_0139
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.971
MCP_2437
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.943
MCP_1640
Conserved hypothetical protein; Contains one Protein of unknown function DUF52 domain (IPR002737); Belongs to the MEMO1 family.
  
    0.908
aspC-2
Aspartate aminotransferase.
  
 0.895
rps2p
30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.893
rnj
Conserved hypothetical protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
  
    0.886
lldP
Putative L-lactate permease.
  
  
 0.850
hmgA-1
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
   
 0.844
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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