STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_1721Putative biotin/lipoate A/B protein ligase. (246 aa)    
Predicted Functional Partners:
MCP_1722
Conserved hypothetical protein.
   
 
 0.982
pdhC
Pyruvate dehydrogenase E2 component.
 
 0.956
lipA
Probable lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.937
pdhB
Pyruvate dehydrogenase E1 component beta subunit.
 
 
 0.907
pdhA
Pyruvate dehydrogenase E1 component alpha subunit.
 
 
 0.830
pdhD
Putative pyruvate dehydrogenase E3 component; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.813
MCP_0970
Putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.796
MCP_1723
Conserved hypothetical protein; Contains one Rhodanese-like domain (IPR001763).
     
 0.783
pycA
Putative pyruvate carboxylase subunit A.
  
  
 0.548
MCP_1724
Putative acyl-CoA synthetase.
     
 0.529
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.