Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
MCP_1750Putative response regulator. (129 aa)    
Predicted Functional Partners:
MCP_1749
NUDIX hydrolase.
     
 0.659
ribL
Putative cytidyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
     
 0.532
MCP_1751
Conserved hypothetical protein; Similar to JAMM-like protein in Archaeoglobus fulgidus (O28085, AF_2198).
       0.523
MCP_1754
Conserved hypothetical protein; Contains at least one CBS domain (IPR000644).
 
     0.521
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
     
 0.515
MCP_1748
Conserved hypothetical protein; Belongs to Type I phosphodiesterase/nucleotide pyrophosphatase family (IPR002591).
       0.499
MCP_0475
Putative response regulator.
 
 
 0.492
MCP_1677
Putative signaling protein; Contains two PAS domains (IPR000014); Contains one PAS-associated, C-terminal domain (IPR000700).; Contains one PAC motif repeat (IPR001610).
 
 
 
 0.477
MCP_2784
Putative histidine kinase; Contains three PAS domains (IPR000014); Contains two PAS-associated, C-terminal domains (IPR000700).; Contains one ATP-binding region, ATPase-like domain (IPR003594).; Contains two PAC motif repeats (IPR001610).
 
 
 
 0.473
hisS
histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.457
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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