Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCP_1809Putative histidine kinase; Contains five PAS domains (IPR000014); Contains five PAS-associated, C-terminal domains (IPR000700).; Contains one ATP-binding region, ATPase-like domain (IPR003594).; Contains five PAC motif repeats (IPR001610). (900 aa)    
Predicted Functional Partners:
MCP_2581
Putative response regulator.
 
 
 0.836
MCP_2698
Protein kinase; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least three Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least five Tetratricopeptide TPR_2repeats (IPR013105).
   
 0.687
MCP_1677
Putative signaling protein; Contains two PAS domains (IPR000014); Contains one PAS-associated, C-terminal domain (IPR000700).; Contains one PAC motif repeat (IPR001610).
 
   
 0.649
MCP_2616
Putative histidine kinase; Contains at least one GAF domain (IPR003018); Contains one ATP-binding region, ATPase-like domain (IPR003594).; Contains one histidine kinase A, N-terminal domain (IPR003661).
   
 0.637
pdhB
Pyruvate dehydrogenase E1 component beta subunit.
   
 0.615
MCP_0475
Putative response regulator.
 
 
 0.607
MCP_0444
Aldo/keto reductase family protein.
   
 0.589
MCP_1768
Putative signaling protein; Contains two PAS domains (IPR000014); Contains two PAS-associated, C-terminal domains (IPR000700).
    
0.550
MCP_1650
Putative response regulator.
 
 
 
 0.513
MCP_1156
Putative response regulator.
 
 
 
 0.479
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.