STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (325 aa)    
Predicted Functional Partners:
MCP_2437
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.966
MCP_0139
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.949
MCP_1818
Conserved hypothetical protein.
       0.751
MCP_1819
Conserved hypothetical protein; Contains one Radical SAMdomain (IPR007197).
       0.735
nusA
NusA protein homolog; Participates in transcription termination. Belongs to the NusA family.
  
    0.700
MCP_0088
Peptidase M50 family protein.
 
  
 0.698
MCP_0056
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.697
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
    
 0.671
MCP_2310
Peptidase M50 family protein.
  
  
 0.634
pyrH
Probable uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.622
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.