Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (325 aa)    
Predicted Functional Partners:
MCP_2437
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.968
MCP_0139
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.952
MCP_1818
Conserved hypothetical protein.
       0.874
MCP_1819
Conserved hypothetical protein; Contains one Radical SAMdomain (IPR007197).
       0.865
MCP_0056
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.782
nusA
NusA protein homolog; Participates in transcription termination. Belongs to the NusA family.
  
    0.704
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
    
 0.660
pyrH
Probable uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.595
argS
arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.594
MCP_0267
Conserved hypothetical protein; Contains one Phosphate acetyl/butaryl transferase domain (IPR002505); Similar to Putative methyltransferase mtx subunit X in Methanosarcina barkeri (strain Fusaro / DSM 804) (O32853).
  
    0.583
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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