STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_1819Conserved hypothetical protein; Contains one Radical SAMdomain (IPR007197). (356 aa)    
Predicted Functional Partners:
MCP_1818
Conserved hypothetical protein.
       0.782
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
       0.735
MCP_1822
Putative purine phosphoribosyltransferase.
 
     0.687
MCP_0291
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF373 family (IPR007254).
 
     0.656
MCP_2746
Putative HTH-type transcriptional regulator.
  
     0.651
MCP_1820
Conserved hypothetical protein.
       0.603
mtnP
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
       0.591
MCP_0638
Putative phosphoadenosine phosphosulfate reductase.
  
     0.579
hjm
Holliday junction migration helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
  
     0.575
MCP_1516
Archaeosine tRNA-ribosyltransferase.
  
     0.574
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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