STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_1835Conserved hypothetical protein; Belongs to the Band 7 protein family (IPR001107); Belongs to the Stomatin family (IPR001972). (368 aa)    
Predicted Functional Partners:
MCP_1836
Conserved hypothetical protein; Belongs to the Nodulation efficiency, NfeD family (IPR002810).
 
  
 0.852
MCP_0377
Peptidase S54, rhomboid family protein; Contains one Zinc finger, AN1-type domain (IPR000058).
  
 0.844
MCP_0300
GTP-binding protein.
  
 0.660
MCP_2698
Protein kinase; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least three Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least five Tetratricopeptide TPR_2repeats (IPR013105).
   
 0.655
pan-1
Proteasome-activating nucleotidase; Belongs to the AAA ATPase family.
  
 
 0.530
pan-2
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 
 0.530
hflX
GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.522
MCP_2722
Conserved hypothetical protein; Contains at least three Pyrrolo-quinoline quinone repeats (IPR002372).
 
 
 0.502
MCP_0006
Conserved hypothetical protein; Contains at least six Pyrrolo-quinoline quinone repeats (IPR002372).
 
 
 0.496
dnaK
Heat shock protein 70; Acts as a chaperone.
  
 0.494
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.