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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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cobDProbable cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (307 aa)    
Predicted Functional Partners:
MCP_1952
L-threonine-O-3-phosphate decarboxylase.
  
 0.997
cobY
Adenosylcobinamide-phosphate guanylyltransferase.
 
  
  0.991
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
   
 0.977
cbiZ
Putative adenosylcobinamide amidohydrolase.
 
  
 0.977
cobB
Probable cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
  
 0.898
MCP_1956
Conserved hypothetical protein.
  
    0.769
MCP_1957
Conserved hypothetical protein; Contains one Elongator protein 3/MiaB/NifB domain (IPR006638); Contains one Radical SAM domain (IPR007197).
       0.762
MCP_1958
Conserved hypothetical protein; Contains one Protein of unknown function DUF102 domain (IPR002805); Belongs to the UPF0284 family.
 
  
 0.752
eif2b
Translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
       0.570
MCP_1094
Putative iron compound ABC transporter ATP binding protein.
 
   
 0.562
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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