Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_1981Conserved hypothetical protein; Contains at least one Cystathionine-beta-synthasedomain (IPR000644); Contains one ParB-like nuclease domain (IPR003115). (279 aa)    
Predicted Functional Partners:
hisE
phosphoribosyl-ATP pyrophosphatase.
       0.888
MCP_1980
Conserved hypothetical protein; Contains one CRS1/YhbY domain (IPR001890).
 
  
 0.637
MCP_2304
Conserved hypothetical protein; Contains two CBS domains (IPR000644).
 
     0.543
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.531
echA
Ech hydrogenase subunit A.
       0.529
gatB
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
  
    0.527
rpl39e
50S ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family.
 
     0.488
MCP_1979
Magnesium-transporting P-type ATPase.
  
    0.479
MCP_0298
Conserved hypothetical protein; Contains two CBS domains (IPR000644).
 
     0.478
MCP_0154
Putative phosphoesterase; Contains one TrkA-N domain (IPR003148).
 
    0.473
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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