node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCP_0636 | MCP_0825 | MCP_0636 | MCP_0825 | Thermosome; Belongs to the TCP-1 chaperonin family. | Conserved hypothetical protein; Contains one Tetratricopeptide TPR_2 repeat (IPR013105). | 0.432 |
MCP_0636 | MCP_2009 | MCP_0636 | MCP_2009 | Thermosome; Belongs to the TCP-1 chaperonin family. | Conserved hypothetical protein; Contains one Heat shock protein DnaJ, N-terminal domain (IPR001623). | 0.690 |
MCP_0636 | MCP_2697 | MCP_0636 | MCP_2697 | Thermosome; Belongs to the TCP-1 chaperonin family. | ATP-dependent Clp protease ATP-binding subunit ClpA homolog. | 0.626 |
MCP_0636 | MCP_2698 | MCP_0636 | MCP_2698 | Thermosome; Belongs to the TCP-1 chaperonin family. | Protein kinase; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least three Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least five Tetratricopeptide TPR_2repeats (IPR013105). | 0.706 |
MCP_0636 | dnaJ | MCP_0636 | MCP_2018 | Thermosome; Belongs to the TCP-1 chaperonin family. | Heat shock protein 40; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | 0.969 |
MCP_0636 | dnaK | MCP_0636 | MCP_2019 | Thermosome; Belongs to the TCP-1 chaperonin family. | Heat shock protein 70; Acts as a chaperone. | 0.993 |
MCP_0636 | grpE | MCP_0636 | MCP_2020 | Thermosome; Belongs to the TCP-1 chaperonin family. | HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependen [...] | 0.949 |
MCP_0664 | MCP_0825 | MCP_0664 | MCP_0825 | Thermosome; Belongs to the TCP-1 chaperonin family. | Conserved hypothetical protein; Contains one Tetratricopeptide TPR_2 repeat (IPR013105). | 0.432 |
MCP_0664 | MCP_2009 | MCP_0664 | MCP_2009 | Thermosome; Belongs to the TCP-1 chaperonin family. | Conserved hypothetical protein; Contains one Heat shock protein DnaJ, N-terminal domain (IPR001623). | 0.690 |
MCP_0664 | MCP_2697 | MCP_0664 | MCP_2697 | Thermosome; Belongs to the TCP-1 chaperonin family. | ATP-dependent Clp protease ATP-binding subunit ClpA homolog. | 0.626 |
MCP_0664 | MCP_2698 | MCP_0664 | MCP_2698 | Thermosome; Belongs to the TCP-1 chaperonin family. | Protein kinase; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least three Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least five Tetratricopeptide TPR_2repeats (IPR013105). | 0.706 |
MCP_0664 | dnaJ | MCP_0664 | MCP_2018 | Thermosome; Belongs to the TCP-1 chaperonin family. | Heat shock protein 40; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | 0.969 |
MCP_0664 | dnaK | MCP_0664 | MCP_2019 | Thermosome; Belongs to the TCP-1 chaperonin family. | Heat shock protein 70; Acts as a chaperone. | 0.993 |
MCP_0664 | grpE | MCP_0664 | MCP_2020 | Thermosome; Belongs to the TCP-1 chaperonin family. | HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependen [...] | 0.949 |
MCP_0825 | MCP_0636 | MCP_0825 | MCP_0636 | Conserved hypothetical protein; Contains one Tetratricopeptide TPR_2 repeat (IPR013105). | Thermosome; Belongs to the TCP-1 chaperonin family. | 0.432 |
MCP_0825 | MCP_0664 | MCP_0825 | MCP_0664 | Conserved hypothetical protein; Contains one Tetratricopeptide TPR_2 repeat (IPR013105). | Thermosome; Belongs to the TCP-1 chaperonin family. | 0.432 |
MCP_0825 | MCP_2009 | MCP_0825 | MCP_2009 | Conserved hypothetical protein; Contains one Tetratricopeptide TPR_2 repeat (IPR013105). | Conserved hypothetical protein; Contains one Heat shock protein DnaJ, N-terminal domain (IPR001623). | 0.935 |
MCP_0825 | MCP_2307 | MCP_0825 | MCP_2307 | Conserved hypothetical protein; Contains one Tetratricopeptide TPR_2 repeat (IPR013105). | Thermosome; Belongs to the TCP-1 chaperonin family. | 0.432 |
MCP_0825 | MCP_2697 | MCP_0825 | MCP_2697 | Conserved hypothetical protein; Contains one Tetratricopeptide TPR_2 repeat (IPR013105). | ATP-dependent Clp protease ATP-binding subunit ClpA homolog. | 0.724 |
MCP_0825 | MCP_2698 | MCP_0825 | MCP_2698 | Conserved hypothetical protein; Contains one Tetratricopeptide TPR_2 repeat (IPR013105). | Protein kinase; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least three Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least five Tetratricopeptide TPR_2repeats (IPR013105). | 0.999 |