STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2066Conserved hypothetical protein; Belongs to the Protein of unknown function DUF371 family (IPR007171). (154 aa)    
Predicted Functional Partners:
MCP_2067
Conserved hypothetical protein.
       0.773
comB
Putative 2-phosphosulfolactate phosphatase.
   
    0.702
MCP_2065
Belongs to the Uncharacterised conserved protein UCP015877, zinc finger family (IPR012041).
 
     0.681
tfe
Transcription initiation factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comple [...]
  
   
 0.639
tiaS
Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
    0.558
MCP_2063
Peptidase M54 archaemetzincin family protein.
  
     0.554
cmk
Cytidylate kinase.
  
     0.547
pcm
protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
       0.545
MCP_0919
Conserved hypothetical protein.
  
     0.534
fwdD-1
Tungsten-containing formylmethanofuran dehydrogenase subunit D.
  
     0.492
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.