Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
secEProtein transport protein SEC61 gamma subunit homolog; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (69 aa)    
Predicted Functional Partners:
secY
Protein transport protein SEC61 subunit alpha homolog; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.951
spt5
Putative ribosomal protein L26e; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
  
 0.943
rpl31e
50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
  
   0.936
rps19e
30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
   0.916
rpl11p
50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
   0.913
rplX
50S ribosomal protein LX.
  
   0.910
rpl32e
50S ribosomal protein L32e.
   
   0.885
rpl15e
50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
   
   0.885
rpl44e
50S ribosomal protein L44E; Binds to the 23S rRNA.
   
   0.884
rps28e
30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
   
 
 0.883
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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