STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2246Conserved hypothetical protein; Belongs to the Protein of unknown function DUF106, transmembrane family (IPR002809). (216 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase.
       0.800
truB
Probable tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
       0.800
secY
Protein transport protein SEC61 subunit alpha homolog; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
    0.792
rps5p
30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
    0.692
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
       0.690
MCP_0003
Conserved hypothetical protein.
  
     0.689
MCP_2297
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF1621 family (IPR012426).
 
     0.689
MCP_0048
Conserved hypothetical protein.
  
     0.688
MCP_0020
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF1119, archaea family (IPR010545).
  
     0.685
MCP_2705
Putative oligosaccharyl transferase.
  
     0.684
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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