Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
MCP_2296Conserved hypothetical protein; Contains one Uncharacterized domain 2 (IPR004521). (162 aa)    
Predicted Functional Partners:
rps28e
30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
 
 
 0.870
MCP_2298
Conserved hypothetical protein; Contains one Zinc finger, ZPR1-type domain (IPR004457).
 
    0.834
MCP_2297
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF1621 family (IPR012426).
       0.805
rps4e
30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 
 
 0.783
rps3Ae
30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
   0.767
rps5p
30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 
 
 0.758
rps3p
30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
    
 
 0.757
flpA
rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 
 0.707
rps7p
30S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
    
   0.702
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
   0.697
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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