Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2308Conserved hypothetical protein; Contains one Protein of unknown function DUF521 domain(s) (IPR007506). (405 aa)    
Predicted Functional Partners:
MCP_2309
Belongs to the Uncharacterised conserved protein UCP004966 family (IPR012016); Contains one Protein of unknown function DUF126 domain (IPR002840).
 
 
 0.999
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
  0.912
MCP_2310
Peptidase M50 family protein.
 
     0.911
MCP_1907
Carboxylyase.
 
     0.668
MCP_1494
Conserved hypothetical protein.
 
     0.590
MCP_0090
Conserved hypothetical protein; Belongs to the Protein of unknown function UPF0004 family (IPR005839); Contains one Cobalamin vitamin B12-binding domain (IPR006158).; Contains one Elongator protein 3/MiaB/NifB domain (IPR006638).; Contains one Radical SAM domain (IPR007197).
       0.575
ubiX
Putative aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
       0.536
MCP_2307
Thermosome; Belongs to the TCP-1 chaperonin family.
       0.515
MCP_1914
Putative metal-dependent phosphohydrolase.
       0.502
cobD
Probable cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.463
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.