STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2373Conserved hypothetical protein. (210 aa)    
Predicted Functional Partners:
MCP_1091
Putative endonuclease IV.
  
 
 0.772
MCP_1129
Exodeoxyribonuclease.
  
 0.768
MCP_2214
Conserved hypothetical protein; Contains one Endonuclease/exonuclease/phosphatase domain (IPR005135).
  
 0.768
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
  
 
 0.674
MCP_2418
Putative DNA glycosidase.
   
 
 0.598
MCP_2374
Hypothetical protein.
       0.567
MCP_2372
Putative carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family.
     
 0.554
MCP_2371
Putative cyclase.
       0.538
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
  
 0.460
MCP_2831
Conserved hypothetical protein; Contains one Adenylate/cytidine kinase, N-terminal domain (IPR011769); Belongs to the Protein of unknown function DUF54 family (IPR002739).
  
  
 0.441
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.