Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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psmBProteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (205 aa)    
Predicted Functional Partners:
psmA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.961
pan-1
Proteasome-activating nucleotidase; Belongs to the AAA ATPase family.
  
 0.922
pan-2
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 0.922
MCP_2698
Protein kinase; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least three Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least five Tetratricopeptide TPR_2repeats (IPR013105).
   
 0.888
MCP_0188
Conserved hypothetical protein.
   
 0.865
MCP_1751
Conserved hypothetical protein; Similar to JAMM-like protein in Archaeoglobus fulgidus (O28085, AF_2198).
   
 0.865
MCP_2400
Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108).
     
 0.865
rpl40e
50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.848
MCP_0057
Cell division control protein 48.
  
 0.697
MCP_2815
Cell division control protein 48.
  
 0.697
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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