| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCP_0060 | MCP_2400 | MCP_0060 | MCP_2400 | Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | 0.759 |
| MCP_2400 | MCP_0060 | MCP_2400 | MCP_0060 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | 0.759 |
| MCP_2400 | psmB | MCP_2400 | MCP_2399 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.865 |
| MCP_2400 | rpoA1 | MCP_2400 | MCP_1218 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.802 |
| MCP_2400 | rpoA2 | MCP_2400 | MCP_1219 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.747 |
| MCP_2400 | rpoB1 | MCP_2400 | MCP_1217 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.802 |
| MCP_2400 | rpoB2 | MCP_2400 | MCP_1216 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | DNA-directed RNA polymerase subunit B''; Belongs to the RNA polymerase beta chain family. | 0.732 |
| MCP_2400 | rpoD | MCP_2400 | MCP_2258 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.728 |
| MCP_2400 | rpoE1 | MCP_2400 | MCP_0352 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | DNA-directed RNA polymerase subunit E'. | 0.831 |
| MCP_2400 | rpoE2 | MCP_2400 | MCP_2674 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.759 |
| MCP_2400 | spt5 | MCP_2400 | MCP_2134 | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | Putative ribosomal protein L26e; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.879 |
| psmB | MCP_2400 | MCP_2399 | MCP_2400 | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | 0.865 |
| psmB | rpoD | MCP_2399 | MCP_2258 | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.468 |
| rpoA1 | MCP_2400 | MCP_1218 | MCP_2400 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Conserved hypothetical protein; Contains one KH, type 1 domain (IPR004088); Contains one Beta-lactamase-like domain (IPR001279).; Contains one RNA-metabolising metallo-beta-lactamase domain (IPR011108). | 0.802 |
| rpoA1 | rpoA2 | MCP_1218 | MCP_1219 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA1 | rpoB1 | MCP_1218 | MCP_1217 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA1 | rpoB2 | MCP_1218 | MCP_1216 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit B''; Belongs to the RNA polymerase beta chain family. | 0.999 |
| rpoA1 | rpoD | MCP_1218 | MCP_2258 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.997 |
| rpoA1 | rpoE1 | MCP_1218 | MCP_0352 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit E'. | 0.981 |
| rpoA1 | rpoE2 | MCP_1218 | MCP_2674 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.864 |