Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhCPutative formate transporter. (310 aa)    
Predicted Functional Partners:
MCP_2405
Putative carbonic anhydrase.
 
  
 0.955
fdhB-2
Formate dehydrogenase beta chain.
  
  
 0.924
fdhB-1
Formate dehydrogenase beta chain.
  
  
 0.853
pfdB
Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
    
 
 0.836
pfdA
Prefoldin alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
    
 
 0.784
fdhA-2
Formate dehydrogenase alpha chain.
  
  
 0.783
MCP_1732
Sulfite reductase.
  
  
 0.766
mcrA
Methyl-coenzyme M reductase alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
      
 0.702
MCP_0989
Glutamate synthase.
     
 0.659
MCP_0970
Putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.632
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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